The clinical research data supporting elénzia RESTORE™‘s ingredients is extensive, showcasing meticulous attention to detail and scientific rigour. Through clinical trials, each component’s safety and efficacy have been validated, with studies exploring mechanisms of action, optimal dosages, and potential synergies.

Collagen Type II (Porcine Collagen)

Joint Health & Mobility

Joint pain is a prevalent issue, particularly among older adults, leading to discomfort and hindrance in movement. Cartilage damage, a common culprit, occurs due to the natural wear and tear of the tough, shock-absorbent tissues that cushion bones within the joint. Consequently, when this protective layer is compromised, inflammation and pain ensue. Age-related conditions like osteoarthritis affect many individuals over 45, resulting in pain during walking and stiffness following movement. Similarly, rheumatoid arthritis manifests as pain and stiffness that exacerbate with activity.

Type 2 collagen, a significant protein found in human connective tissues, cartilage, and bones, plays a crucial role in enhancing cartilage strength and elasticity through the formation of amino acid chains. However, as we age, collagen production diminishes, contributing to increased joint stiffness. Collagen, the most abundant protein in the human body, is a key component found in elénzia RESTORE™, specifically, Collagen Type II (Porcine Collagen), which provides strength and elasticity to our joints. Research indicates that Collagen Type II (Porcine Collagen) can effectively reduce joint pain and improve mobility, particularly in individuals suffering from osteoarthritis.

Skin Health

As we age, our skin undergoes significant changes, including thinning, reduced elasticity, and increased fragility. Decreased production of natural oils can lead to dryness, while wrinkles, age spots, and skin tags become more prevalent. Additionally, collagen degradation outpaces its replenishment in aging skin. Factors such as UV damage, smoking, stress, and poor diet can accelerate this decline in collagen levels, exacerbating the aging process.

Protein, a fundamental component present in every cell, constitutes approximately one-third of our body mass. Collagen, the most abundant protein, plays a crucial role in maintaining the integrity of our skin, muscles, bones, and joints, distributed throughout various bodily tissues. Collagen Type II (Porcine Collagen), comprising lengthy chains of amino acids, forms a sturdy framework that facilitates the cohesion of skin cells. However, collagen levels naturally decline with age, beginning around 20 years old and diminishing by roughly 1% annually. This decline affects the skin’s elasticity, reducing the likelihood of sagging or loose skin and promoting a smoother, more youthful appearance. Additionally, collagen helps mitigate and prevent the formation of fine lines and wrinkles, while also maintaining skin hydration for a youthful complexion.

Collagen Type II has been shown to improve skin health through double-blind, randomised, placebo-controlled clinical studies.  

Collagen Type II (Porcine Collagen) emerges as a vital ingredient for joint health and mobility, combating prevalent issues like joint pain and stiffness, particularly in age-related conditions such as osteoarthritis. Moreover, it plays a pivotal role in maintaining skin health, countering the effects of aging such as thinning, reduced elasticity, and dryness. Through its ability to promote skin strength, elasticity, and hydration, Collagen Type II (Porcine Collagen) exemplifies elénzia RESTORE™‘s dedication to holistic well-being, supported by robust clinical evidence.

With a unique combination of natural extracts, elénzia SKIN™ emphasises the interconnectedness of gut and skin, showcasing our commitment to holistic health.

Rosemary and Grapefruit Extract – UV Protection

Skin damage occurs as a consequence of exposure to environmental stressors, such as pollution and UV radiation, leading to adverse effects on skin health and appearance including diminished skin health, poor complexion, and premature aging.

elénzia medical nutritionists have highlighted a clinically proven and unique combination of natural extracts from Mediterranean Rosemary and Grapefruit, aiming to protect the skin from external factors using a holistic approach that extends beyond topical application. 

[Monteloeder 2023, Nobile et al., 2016]

Grape Seed Extract – Skin Radiance

The acceleration of aging and dulling of the skin involves various factors, including both intrinsic elements like natural aging and extrinsic influences such as sun exposure, smoking, and medication usage.

A patent-pending formulation of natural antioxidants, combining French grape seed and melon extracts, bioactive Superoxide Dismutase, vitamin C, and zinc provides optimal antioxidant protection, preventing oxidation, and regulating melanin synthesis, collagen fibres, and microcirculation, unlike most skin anti-aging solutions.

[Dumoulin et al., 2016]

Fibre – Gut-Skin Axis

The Gut-Skin Axis connects gut and skin wellbeing, where imbalances in gut bacteria can lead to pro-inflammatory molecules entering the bloodstream. This process may trigger skin issues like acne, eczema, rosacea, and other skin problems.

Promoting the Gut-Skin axis through prebiotics can play a crucial role in sustaining the health of the outer skin layer, known as the ‘stratum corneum.’ It helps maintain softness, smoothness, hydration, and skin flexibility.

Our formula includes a partially hydrolysed guar fibre, which acts as a prebiotic, positively influencing the gut microbiome and enhancing skin health. These essential metabolites play a key role in maintaining a healthy gut by producing short-chain fatty acids in the gut and elevating acetate, propionate, and butyrate levels in the GI tract. They directly support the cells of the gut lining, promoting cellular integrity, bolstering the protective mucosal layer, and reducing inflammation.

[Kapoor et al., 2023]

In closing, elénzia SKIN™ is the result of rigorous clinical research, offering evidence-backed results for enhanced skin health. From UV protection to skin radiance, our formula addresses various factors contributing to aging. The holistic approach extends to the Gut-Skin Axis, promoting gut health through prebiotics for overall well-being.

The development of elénzia PROTEIN™, a plant-based protein peptide supplement, is grounded in a thorough examination of clinical research data. Drawing from a wealth of scientific studies, the formulation process integrates cutting-edge research findings to optimise the blend of plant-derived peptides, ensuring efficacy and bioactive properties.

Protein Composition

Proteins are the building blocks of your bodily tissues including muscle, skin and hair. Having an adequate intake for your personal needs is vital to maintain optimum health. Proteins are composed of amino acids and 9 of these cannot be made by our body.

Vegan protein sources tend to be ‘incomplete’ and lack at least 1 of these essential amino acids. So, a beneficial combination of vegan proteins is required to provide a complete source of all essential amino acids.

elénzia PROTEIN™ beneficially combines pea and rice proteins to provide a complimentary amino acid profile covering all the essential amino acids for optimum health and function.

Therefore, this product is a complete vegan protein source (Hertzler et al., 2020).

Pea protein, in particular, is an excellent vegan source of Branched Chain Amino Acids (BCAA’s). These three essential amino acids – leucine, isoleucine, and valine – are vital for Muscle Protein Synthesis. An insufficient BCAA intake would impact recovery time and muscle mass maintenance, even leading to muscle wastage. A meta-analysis of 8 studies that considered the effect of BCAA supplementation on post-exercise muscle soreness found a large and significant reduction in soreness compared to a placebo (Fedewa et al., 2019).

Digestibility

Plant-based protein sources are notorious for their lower digestibility. Intact cell walls shield the intracellular proteins from digestive enzymes, preventing efficient digestion, absorption, and total availability to the body. (Roelofs et al., 2024)

However, pea and rice proteins are not simply isolated from the other cellular components, they are pre-digested or hydrolysed. As the initial breakdown of the protein is already complete, its digestion and absorption rate are improved, providing high bioavailability (Koopman et al., 2009).

Weight management

Maintaining a high-protein diet is vital for those seeking sustainable weight loss. Adequate protein intake prevents lean muscle mass loss during periods of restricted calorie intake (Moon & Koh, 2020).

Evans et al. (2012) carried out a randomised clinical trial over 12 months where 130 overweight individuals either consumed a high protein diet or simply a calorie restriction diet. Incredibly, individuals whose diet had a relatively high ratio of protein (the high protein group) lost 53% more weight than those who restricted calorie intake.

Satiety

By increasing levels of GLP-1 and leptin in the body and inhibiting the hunger hormone ‘Ghrelin’, increasing protein intake helps us feel satisfied for longer and reduces the incidence of snacking. (Moon & Koh, 2020).

Weigle et al., (2005) Carried out a weight loss study on overweight women and found that those consuming a diet with protein accounting for 30% of calories instead of only 15% consumed an average of 441 calories less per day. So, consuming more protein as part of our meals is more satiating and can help the natural reduction in calorie intake throughout the day.

Interestingly, a study by Diepvens et al., (2007) found that pea protein hydrolysates were more effective at suppressing hunger than whey protein. Therefore, elénzia PROTEIN™ may have a greater impact on satiety and daily calorie consumption, highlighting its potential as a weight management product.

The convenience and concentrated dose of elénzia PROTEIN™ can help individuals trying to increase their daily protein intake and reap the benefits.

Vitamins & Minerals

Vitamin D2  – contributes to the maintenance of normal muscle function and the normal function of the immune system.

Vitamin B2 – contributes to normal energy-yielding metabolism and the normal metabolism of iron.

Vitamin B3 – contributes to normal energy-yielding metabolism and the reduction of tiredness and fatigue.

Vitamin B5 – contributes to the reduction of tiredness and fatigue and the normal synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters.

Vitamin B6 – contributes to normal protein and glycogen metabolism and the reduction of tiredness and fatigue.

Vitamin B12  – contributes to normal energy-yielding metabolism and the reduction of tiredness and fatigue.

Vitamin C – contributes to maintaining the normal function of the immune system during and after intense physical exercise and increases iron absorption.

Iron – contributes to normal energy-yielding metabolism, the reduction of tiredness and fatigue and the normal function of the immune system.

Selenium – contributes to the normal function of the immune system and the normal thyroid function.

Zinc – contributes to normal protein synthesis, the normal function of the immune system and the protection of cells from oxidative stress.

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This in-depth analysis of clinical research data served as the cornerstone for developing elénzia MENOPAUSE™. It involves a fusion of cutting-edge scientific advancements with a profound comprehension of women’s health needs during this crucial stage. The formulation integrates a unique blend of natural compounds, carefully selected and balanced, aiming to alleviate symptoms and support the overall wellbeing of women during all stages of menopause.

Spearmint Polyphenol Extract – Brain Function, Memory & Focus

The decline in oestrogen levels during menopause directly impacts women’s brain health, affecting aspects such as working memory and focus, as oestrogen plays a crucial role in both ovary and brain function.

elénzia medical nutritionists have researched ingredients for proven efficacy and have selected the polyphenol composition from a specific  Spearmint Polyphenol extract that is clinically proven to improve cognitive function and support adult working memory.

Found in MENOPAUSE: AM

Sage Leaf Extract – Hot Flashes

During menopause, the decrease in oestrogen levels leads to the occurrence of hot flashes, as oestrogen fluctuation influences the body’s temperature regulation mechanism.

An extract from Sage Leaf (Salvia Officinalis L.) has been shown to improve cognitive performance within an hour. Sage increases neurotransmitter levels, including monoamines like dopamine and serotonin, which increase thermoregulation in menopausal women.

Found in MENOPAUSE: AM, MENOPAUSE: PM

Vitamin D and K2-7 – Bones, Joints and Teeth

Menopause affects bone and joint health by increasing osteoporosis risk due to reduced oestrogen levels. This decrease can cause osteopenia (reduced bone mass) and potentially lead to increased fracture susceptibility and overall bone weakness, impacting joint health.

Vitamin D and K2-7 are essential for building strong bones and teeth, promoting calcium absorption and utilisation, maintaining blood calcium levels, promoting healthy bone formation, and preserving muscular function.

Found in MENOPAUSE: AM, MENOPAUSE: PM

Collagen Peptides – Skin Structure

The reduction in collagen production as we age, coupled with decreased skin hydration, particularly in hyaluronic acid levels, hampers the body’s ability to repair damaged skin, leading to noticeable skin changes and aging.

Collagen is a protein that fuses the structural connective tissue throughout the body, from the skin to bones, muscles, tendons and ligaments.

Found in MENOPAUSE: AM, MENOPAUSE: PM

Lemon Verbena Extract – Sleep Quality

The declining levels of oestrogen and progesterone during menopause often prompt lifestyle changes, particularly impacting sleep patterns. Decreasing progesterone, a hormone associated with sleep, may cause difficulty falling and staying asleep.

Lemon Verbena is a botanical rich in phenylpropanoids and flavones, which when extracted, have been scientifically proven to alleviate insomnia and anxiety symptoms.

At 400mg, Lemon Verbena extract enhances sleep quality and reduces anxiety by lowering cortisol levels, resulting in fewer interruptions, longer sleep time and REM.

Found in MENOPAUSE: PM

In conclusion, elénzia MENOPAUSE™ stands at the intersection of scientific innovation and a deep understanding of women’s health needs during the critical stages of menopause. This meticulously formulated product, enriched with Spearmint Polyphenol extract for brain function, Sage Leaf extract for hot flashes, Vitamin D and K2-7 for bone and joint health, Collagen Peptides for skin structure, and Lemon Verbena extract for improved sleep quality, offers comprehensive support to help women navigate the diverse challenges that come with this transformative phase of life.

With a holistic approach to wellbeing, elénzia MENOPAUSE™ strives to empower women and enhance their overall quality of life during menopause and beyond.